MkMPs or CMPs resuspended in PBS were first diluted 140-fold in deionized water. Their size distribution was measured by NTA using NanoSight NS300 (Malvern). Each analysis was carried out with five measurements, with the camera level set at 9 to 10, the detection threshold at 4, and 50 to 80 particles per frame with 1500 frames per measurement.

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