General information
This protocol is extracted from research article:
Rhodium-catalyzed, P-directed selective C7 arylation of indoles
Sci Adv, Dec 14, 2018; DOI: 10.1126/sciadv.aau6468

Unless otherwise noted, all reactions were performed under an argon atmosphere using a flame-dried glassware. Toluene, chlorobenzene, and m-xylene were distilled over CaH2. All new compounds were fully characterized. NMR spectra were recorded on a Bruker AV-300, an ARX-400 MHz, or an ARX-600 Associated. 1H NMR spectra data were reported as δ values in parts per million (ppm) relative to chloroform (δ = 7.26) if collected in CDCl3. 13C NMR spectra data were reported as δ values in ppm relative to chloroform (δ = 77.0) if collected in CDCl3. Mass spectrometry was conducted with the Micromass Q-TOF Instrument (ESI) and Agilent Technologies 5973N (EI). All reactions were carried out in flame-dried 25-ml Schlenk tubes with Teflon screw caps under argon. Rh(PPh3)3Cl and [Rh(cod)Cl]2 were purchased from J&K. Unless otherwise noted, materials obtained from commercial suppliers were used without further purification.

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