To analyze measurement data (means ± SEM), Student’s t test was used for comparisons between two groups, and one-way ANOVA, followed by Tukey’s test, was used for comparisons between three groups. As the patch-clamp recordings were performed before and after treatment, the effect of each treatment was normalized to the baseline and analyzed using the paired t test. The χ2 test was used to compare sex differences between the epileptic patients and controls. The Mantel-Cox log rank test was used to compare percent survival over time. P < 0.05 was considered statistically significant.

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