Operation of an ionic decision-maker for DMBPs with one device and two channels
This protocol is extracted from research article:
Ionic decision-maker created as novel, solid-state devices
Sci Adv, Sep 7, 2018; DOI: 10.1126/sciadv.aau2057

The ionic decision-maker device was placed in a manual probe system and connected using two tungsten probes, as shown in Fig. 1D. The electrochemical cell was connected to a potentio/galvanostat (CompactStat, Ivium Technologies), which was controlled using custom software designed to generate a random number and initiate a current application at positive or negative 500 nA for 500 ms. A random number was generated to emulate stochastic events using various values of Pi. For example, a random number from 0 to 1 was generated, and if it was smaller than Pi, it was interpreted as transmitted, and a positive 500 nA was applied for 500 ms. If the generated number was larger than Pi, it was interpreted as blocked, and a negative 500 nA was applied for 500 ms.

The operation was composed of 800 selections, with each selection being repeated for 100 cycles. Each cycle started with a short circuit of the two electrodes for 200 s to refresh the electrochemical cell (refreshment stage). The circuit was opened, and the voltage was measured to identify the signal of the voltage (positive or negative). When the voltage was positive, channel A was selected. The selection was emulated by random number generation with PA and the subsequent current application, as described above, and vice versa. After current application, the circuit was opened for 500 ms to measure the voltage. Each unit of operation was a selection. After every 200 repetitions of the selections, the PA and PB values were inverted to emulate environmental changes. After 800 consecutive selections with three inversions (that is, one cycle), the operation moved to the refreshment stage of the next cycle. One hundred cycles were performed for each PA/PB combination.

Note: The content above has been extracted from a research article, so it may not display correctly.

Please log in to submit your questions online.
Your question will be posted on the Bio-101 website. We will send your questions to the authors of this protocol and Bio-protocol community members who are experienced with this method. you will be informed using the email address associated with your Bio-protocol account.

We use cookies on this site to enhance your user experience. By using our website, you are agreeing to allow the storage of cookies on your computer.