A 25-ml stainless steel autoclave with mechanical stirrer was loaded with 50 mg of catalyst and 10 ml (7.0584 g, 62.9 mmol) of substrate, which was dried over Na and freshly distilled. The autoclave was closed and flushed with H2 three times. H2 (40 bar) was charged, and the autoclave was heated to 150°C with an aluminum block and stirred properly. When the pressure dropped to around 5 bar, it was readjusted to 40 bar. After the denoted reaction time, the autoclave was cooled with an ice bath and the pressure was carefully released. The mixture was filtered through a filter paper into a round bottom flask (6.843 g, 59.9 mmol, 95%). Mesitylene was added as internal standard, and 1H NMR was measured.

Note: The content above has been extracted from a research article, so it may not display correctly.

Please log in to submit your questions online.
Your question will be posted on the Bio-101 website. We will send your questions to the authors of this protocol and Bio-protocol community members who are experienced with this method. you will be informed using the email address associated with your Bio-protocol account.

We use cookies on this site to enhance your user experience. By using our website, you are agreeing to allow the storage of cookies on your computer.