Microarray analysis was performed with Mouse 430.2 gene chips (Affymetrix) at the OHSU Gene Profiling Shared Resource, and data were analyzed using GeneSifter software (Geospiza) to identify relative expression differences between cell types (replicates: MФ, n = 3; MC38, n = 3; hybrids, n = 5 independent isolates) and produce GO analyses. GO category enrichment was calculated using the GOstats R package (53) and visualized using functions from the GOplot R package (54).

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