Seven resting-state networks from Yeo and colleagues (19) were considered. Each network was spatially distributed, e.g., the red default network (Fig. 2C) has separate components in the lateral parietal cortex, posterior cingulate/precuneus, lateral temporal cortex, medial prefrontal cortex, and so on. A connected component analysis was used to extract all the connected “islands” of each network. Small components (less than eight vertices) were reassigned to the most correlated networks. Furthermore, vertices whose neighbors belonged to a different component were removed. This resulted in a final set of 51 parcels.

It is worth noting that the use of the Desikan-Killiany atlas for the MFM followed previous applications of the MFM (7, 14). The resting-state ROIs were not directly used for the MFM because some of the ROIs were small and narrow. As such, the tractography estimates would not be reliable for these small ROIs. Furthermore, results were replicated using the Lausanne 2008 parcellation, suggesting that the results were robust to the exact choice of parcellation.

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