This RCT is registered with the publicly accessible www.clinicaltrials.gov registry for dissemination and data sharing purposes. RCT results will be published in a high-impact, peer-reviewed journal no more than 12 months after the end of the participant 18-month assessment visits and made freely available for public access within 6 months of publication. We expect to prepare up to ten publications addressing the different facets of this work. We will also present our results at national or international scientific conferences. We will disseminate our study findings on our website, in letters to the editor, participation in online journal clubs, through Alberta Health Services (AHS) newsletters, and internal publications at the University of Calgary and AHS. Similar routes will disseminate the results to other knowledge user team members and partners. Data and biological samples collected during this RCT will be made available to other qualified researchers with the informed consent of participants; data and samples will be de-identified to protect participant confidentiality and privacy.

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