SPSS software (version no. 17.0, IBM, CHI, USA) was used to analyze the data. Multiple comparisons were performed using one-way ANOVA. Independent sample T test was used to compare the difference of KDF1 mRNA expression level between the tumor tissue of ccRCC patients and that of the normal controls. Other differences between two groups in the present study were compared by using Mann-Whitney U test. The Spearman correlation analysis was used to explore the correlation of KDF1 mRNA and protein level (represented by score) with the clinicopathological indices. The Kaplan–Meier method and log-rank test were used for survival analysis. The Cox proportional hazards model was used to determine which variables influenced survival. The variables that significantly impacted survival in univariate analyses were included in multivariate analyses. All statistical tests were two tailed, and P values <0.05 were considered significant.

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