The study included all patients aged ≥18 years, who were identified from SIA/SUS database, received SGAs (clozapine, olanzapine, quetiapine, risperidone, or ziprasidone) for more than 90 days, during January 2008 to December 2017, and diagnosed with one of the following diseases according to International Statistical Classification of Diseases and Related Health Problems, Tenth Revision (ICD-10): Paranoid schizophrenia (F20.0), Hebephrenic schizophrenia (F20.1), Catatonic schizophrenia (F20.2), Undifferentiated schizophrenia (F20.3), Post-schizophrenic depression (F20.4), Residual schizophrenia (F20.5), Simple schizophrenia (F20.6), Other schizophrenia (F20.8), Schizoaffective disorder, manic type (F25.0), Schizoaffective disorder, depressive type (F25.1), Schizoaffective disorder, depressive type (F25.2).

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