The following baseline data of all the participants were collected: gender, age, height, weight, and the duration of the disease. Hoehn & Yahr (H-Y) stage and UPDRS were used to assess the motor symptoms. To assess the non-motor symptoms, we used the Non-motor symptoms Scale (NMSS). Parkinson's Disease Sleep Scale (PDSS) and Pittsburgh sleep quality index (PSQI) were applied to evaluate the patients' sleep quality. Cognitive function was assessed using the Montreal Cognitive Assessment (MoCA) and Mini-mental State Examination (MMSE). The quality of life was evaluated using the Parkinson's Disease Questionnaire-39 (PDQ39). Severity of anxiety and depression were quantified by the Hamilton Depression Scale (HAMD) and Hamilton Anxiety Scale (HAMA), respectively.

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