CRC-associated miRNAs were identified in the dbDEMC 2.0 (21) and miRCancer (22) databases. These databases were also used to find the tripartite overlapping data of differentially expressed miRNAs and miRNAs associated with CRC using Biovenn (23). The target genes of differentially expressed miRNAs were predicted by the PicTar (24), Targetscan (25) and miRanda (26) databases. The cut-off value determined using mirSVR was −0.49. The regulatory network of miR-142-3p and its targeted genes were visualized using Cytoscape (27). Tripartite overlapping genes were identified, and enriched pathways and cellular functions were identified by Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) analyses ( using the Database for Annotation, Visualization, and Integrated Discovery (DAVID) v6.8 (28).

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