K562 cells were divided into a normoxic group (21% O2, 5% CO2, 37°C, saturation humidity) and a hypoxic group (1% O2, 5% CO2, 94% N2, 37°C, saturation humidity). Hemin was added (40 mM/l; 37°C; Beijing Solarbio Science & Technology Co., Ltd.), and incubation was performed for 96 h.

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