To a cooled solution (about −70 °C isopropyl alcohol and dry ice) of 10 (500 mg, 1.08 mmol) in 20 mL THF was added imidazole (235.39 mg, 3.46 mmol) and TBDPSCl (445.48 mg, 1.62 mmol, d = 1.057 g/mL). When the temperature reached ambient temperature, the mixture was further stirred for 24 h. Next, the solvent was evaporated under reduced pressure and the obtained oily residue was purified by column chromatography (H:OAc 20:1→5:1 v/v) to give 370 mg (49%) of ketone 11 as a light straw-colored oil.

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