Education
Ph.D. in Immunology, Université René Descartes Paris V, 1996
Current position
DR2 (CNRS), U1013, Hopital Necker, Paris, France
Publications (since 2005)
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Tohme, M., Maschalidi, S. and Manoury, B. (2013). In vitro digestion with proteases producing MHC class II ligands. Methods Mol Biol 960: 509-515.
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Maschalidi, S., Hassler, S., Blanc, F., Sepulveda, F. E., Tohme, M., Chignard, M., van Endert, P., Si-Tahar, M., Descamps, D. and Manoury, B. (2012). Asparagine endopeptidase controls anti-influenza virus immune responses through TLR7 activation. PLoS Pathog 8(8): e1002841.
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Apcher, S., Manoury, B. and Fahraeus, R. (2012). The role of mRNA translation in direct MHC class I antigen presentation. Curr Opin Immunol 24(1): 71-76.
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Weimershaus, M., Maschalidi, S., Sepulveda, F., Manoury, B., van Endert, P. and Saveanu, L. (2012). Conventional dendritic cells require IRAP-Rab14 endosomes for efficient cross-presentation. J Immunol 188(4): 1840-1846.
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Descamps, D., Le Gars, M., Balloy, V., Barbier, D., Maschalidi, S., Tohme, M., Chignard, M., Ramphal, R., Manoury, B. and Sallenave, J. M. (2012). Toll-like receptor 5 (TLR5), IL-1beta secretion, and asparagine endopeptidase are critical factors for alveolar macrophage phagocytosis and bacterial killing. Proc Natl Acad Sci U S A 109(5): 1619-1624.
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Guery, L., Benikhlef, N., Gautier, T., Paul, C., Jego, G., Dufour, E., Jacquel, A., Cally, R., Manoury, B., Vanden Berghe, T., Vandenabeele, P., Droin, N. and Solary, E. (2011). Fine-tuning nucleophosmin in macrophage differentiation and activation. Blood 118(17): 4694-4704.
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Manoury, B. (2011). TLR9 regulation by proteolysis: a friend or a foe. Eur J Immunol 41(8): 2142-2144.
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Apcher, S., Daskalogianni, C., Lejeune, F., Manoury, B., Imhoos, G., Heslop, L. and Fahraeus, R. (2011). Major source of antigenic peptides for the MHC class I pathway is produced during the pioneer round of mRNA translation. Proc Natl Acad Sci U S A 108(28): 11572-11577.
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Apcher, S., Daskalogianni, C., Manoury, B. and Fahraeus, R. (2010). Epstein Barr virus-encoded EBNA1 interference with MHC class I antigen presentation reveals a close correlation between mRNA translation initiation and antigen presentation. PLoS Pathog 6(10): e1001151.
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Sepulveda, F. E., Maschalidi, S., Colisson, R., Heslop, L., Ghirelli, C., Sakka, E., Lennon-Dumenil, A. M., Amigorena, S., Cabanie, L. and Manoury, B. (2009). Critical role for asparagine endopeptidase in endocytic Toll-like receptor signaling in dendritic cells. Immunity 31(5): 737-748.
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Le Roux, D., Lankar, D., Yuseff, M. I., Vascotto, F., Yokozeki, T., Faure-Andre, G., Mougneau, E., Glaichenhaus, N., Manoury, B., Bonnerot, C. and Lennon-Dumenil, A. M. (2007). Syk-dependent actin dynamics regulate endocytic trafficking and processing of antigens internalized through the B-cell receptor. Mol Biol Cell 18(9): 3451-3462.
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Vascotto, F., Lankar, D., Faure-Andre, G., Vargas, P., Diaz, J., Le Roux, D., Yuseff, M. I., Sibarita, J. B., Boes, M., Raposo, G., Mougneau, E., Glaichenhaus, N., Bonnerot, C., Manoury, B. and Lennon-Dumenil, A. M. (2007). The actin-based motor protein myosin II regulates MHC class II trafficking and BCR-driven antigen presentation. J Cell Biol 176(7): 1007-1019.
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Watts, C., Matthews, S. P., Mazzeo, D., Manoury, B. and Moss, C. X. (2005). Asparaginyl endopeptidase: case history of a class II MHC compartment protease. Immunol Rev 207: 218-228.
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Murray, J., Manoury, B., Balic, A., Watts, C. and Maizels, R. M. (2005). Bm-CPI-2, a cystatin from Brugia malayi nematode parasites, differs from Caenorhabditis elegans cystatins in a specific site mediating inhibition of the antigen-processing enzyme AEP. Mol Biochem Parasitol 139(2): 197-203.