Jiazhi Hu
  • Faculty, Peking university
Research focus
  • Immunology
  • Immunology、DNA damage and repair
Lab Protocol Hub

Education

Ph.D, Peking University, 2012

Lab information

Jiazhi Hu lab

Publications

1.Zuo E#, Huo X#, Yao X#, Hu X#, Sun Y#, Yin J#, He B, Wang X,
Shi L, Ping J, Wei Y, Ying W, Wei W, Liu W, Tang C, Li Y, Hu J* & Yang H*. (2017). CRISPR/Cas9-mediated targeted chromosome elimination. Genome Biology 18:224. doi: 10.1186/ s13059-017-1354-4.
https://genomebiology.biomedcentral.com/articles/10.1186/s13059-017-1354-4
2.Lin SG#, Ba Z#, Du Z#, Zhang Y, Hu J* & Alt FW*. (2016). A highly sensitive and unbiased approach for elucidating antibody repertoires. Proc Natl Acad Sci USA 113(28):7846-51. doi: 10.1073/pnas.1608649113.
http://www.pnas.org/content/113/28/7846
3.Hu J#, Meyers RM#, Dong J, Panchakshari RA, Alt FW* & Frock RL*. (2016). Detecting DNA double-stranded breaks in mammalian genomes by linear amplification-mediated high- throughput genome-wide translocation sequencing. Nature Protocols 11(5): 853-71. doi: 10.1038/nprot.2016.043.
https://www.nature.com/articles/nprot.2016.043
4.Hu J#, Zhang Y#, Zhao L, Frock RL, Du Z, Meyers RM, Meng F- L, Schatz DG, & Alt FW. (2015). Chromosomal loop domains direct the recombination of antigen receptor genes. Cell 163(4): 947-59. doi: 10.1016/j.cell.2015.10. 016.
https://www.cell.com/cell/fulltext/S0092-8674(15)01330-6
5.Frock RL#, Hu J#, Meyers RM, Ho Y-J, Kii E, & Alt FW. (2015). Genome-wide detection of DNA double-stranded breaks induced by engineered nucleases. Nature Biotechnology 33(2):179-86. doi: 10.1038/nbt.3101.
https://www.nature.com/articles/nbt.3101
6.Hu J#, Tepsuporn S#, Meyers RM, Gostissa M*, & Alt FW*. (2014). Developmental propagation of V(D)J recombination- associated DNA breaks and translocations in mature B cells via dicentric chromosomes. Proc Natl Acad Sci USA 111(28): 10269-74. doi: 10.1073/pnas.1410112111.
http://www.pnas.org/content/111/28/10269.long
7.Hu J, Sun L, Shen F, Chen Y, Hua Y, Liu Y, Zhang M, Hu Y, Wang Q, Xu W, Sun F, Ji J, Murray JM, Carr AM, & Kong D. (2012). The intra-S phase checkpoint pathway targets Dna2 to prevent stalled replication forks from reversing. Cell 149(6): 1221-32. doi: 10.1016/j.cell.2012.04.030.
https://www.cell.com/cell/fulltext/S0092-8674(12)00575-2
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