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Each biomarker or biomarker combination with either diagnostic, prognostic, or risk value was defined as a biomarker entry. Some manuscripts had multiple biomarker entries, resulting in several biomarker entries per paper. For example, if a single biomarker was tested in three ways—(1) predicting the development of later TA-TMA, (2) diagnostic ability, and (3) association of later non-relapsed related mortality (prognosis)—this resulted in three biomarker entries.
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